![]() ![]() However, this is unstable, and the electrons fall back down to lower states, emitting the difference in energy as a photon of light of a different wavelength. When they shone light of a certain wavelength onto the sample, electrons in the molecules used that energy to jump to excited states. First, the researchers mixed the samples with a solution containing silver nanoparticles, so that fluorescence could occur. The measurement uses a technique called spectrofluorimetry, which measures the wavelength of light given off by fluorescent molecules when light of a different wavelength shines on them. “Finding better, precise, easy to use, and cheap ways for measuring the drugs in the human body or biological samples is of great importance to me.” “I am an analytical chemist who is interested in the use of chemistry to improve the quality of human life,” said Lotfi. ![]() The technique was developed by Ali Lotfi and his colleagues at the Islamic Azad University and the Tabriz University of Medical Sciences, both in Tabriz, Iran. A new technique, published in the Journal of Luminescence, offers a rapid and sensitive method to measure the levels of the SSRI sertraline in human urine, blood and pharmaceuticals. In order to monitor the effects of these drugs, clinicians need to know what levels of the drugs are in a patient’s body. SSRIs ease the symptoms of depression by increasing levels of serotonin in the brain, but they have many potential side effects, including nausea, dizziness and insomnia. In recent years, selective serotonin reuptake inhibitors (SSRIs) have become the number one choice in drugs for depression treatment. ![]() As the biggest killer of 16 to 25 year olds in the world, finding ways to treat this common disorder is an important goal for pharmaceutical companies. More than 300 million people across the globe suffer from depression. The new technique mixes samples with a solution containing silver nanoparticles, and uses a method called spectrofluorimetry. New technique helps measure the concentration of antidepressants in the human body ![]()
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